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09/11/2024

The Atlas of Social Complexity. Chapter 14: Psychopathology of mental disorders

As I stated in my previous post, the second major content theme in The Atlas ofSocial Complexity is the Dynamics of Human Psychology. So far for this theme, I’ve given a basic overview, found here. I then moved on to the first theme, Humanpsychology as dynamical system (Chapter 13).

 

The focus of this post is Chapter 14: Psychopathology of mental disorders.

 

 

OVERVIEW OF CHAPTER

Chapter 14 explores the question: What is a mental disorder and how best should we assess it in terms of social complexity? 

 

The field of psychopathology (also sometimes referred to as abnormal psychology) is the formal term for the study of mental disorders. Subfields include developmental, child, adolescent, and adult psychopathology. The general focus across all these sub-fields is on ‘abnormal’ states of thinking, feeling and behaving, particularly within a clinical context – with an awareness that our conceptualisation of what is ‘abnormal’ is deeply connected to our interpersonal relationships, community, culture and sociohistorical context. 

 

There is general agreement that, when it comes to psychopathology, what matters most is that a person is legitimately troubled by their emotional, cognitive, behavioural or social difficulties. In short, they are suffering.

 

There is less agreement, however, on what constitutes a mental disorder. For example, are a person’s psychological difficulties a brain disease or latent psychological construct? Or are they a scientific classification that points to the clustering of sets of psychological symptoms that have no fundamental underlying biological existence? The former view has historically dominated. The latter – referred to as the new science of mental disorders – is fast becoming the major alternative, with the potential to override the former.  


Mental Health Symptom Networks

The network science of psychopathology got its start in the Psychology Department at the University of Amsterdam with the publication of two key articles. The first, in 2008, was Denny Borsboom’s Psychometric perspectives on diagnostic system. While breaking new ground, the concept of networks remained unarticulated in it. A more complete statement arrived with the second publication, in 2010, led by Angélique Cramer.[1] It is at this point that this approach really takes off.

 

It is fitting that the title of Cramer and colleagues’ article is Comorbidity: A network perspective, as symptom overlap is one of the primary reasons the network approach was created. As Robinaugh and colleagues state, “The network approach to psychopathology began a decade ago with a simple hypothesis: symptoms may cohere as syndromes because of causal relations among the symptoms themselves”.[2] From this perspective, they explain, “symptoms are not passive indicators of a latent ‘common cause’; they are agents in a causal system”. [3] Despite the significant advance over the last 13 years, the idea of mental disorders being a collection of symptoms, many of which are shared by or part of the symptom networks of other mental disorders, remains central for this approach. There is no underlying latent construct and no single-cause explanation for any mental health diagnostic category. There are only symptoms.

 

During the next thirteen years, the network approach would quickly become a major contender for the definition and diagnosis of psychopathology as well as a counterpoint to conventional approaches in psychometrics, with articles being published widely. Symptom network analysis has been applied to depression, schizophrenia, post-traumatic stress disorder, anxiety, psychosis, sleep disorders, autism, bipolar disorder, and a variety of comorbid mental health conditions.

 

This widespread adoption is demonstrated well by the fact that Cramer and colleagues published a second article in Behavioral and Brain Sciences in 2019[4].

 

Controversies, Challenges and an Agenda for Moving Forward

 

When the symptom network approach to psychopathology first emerged, its novelty was its virtue. Here, suddenly, was a way to use the latest advances in complex network analysis to think about mental disorders that felt authentic to clinical intuitions and experience.  Research collided with practice, a rare event.

 Nevertheless, there are a list of challenges that need to be addressed. Here is a list of the topics addressed in Chapter 14.

1. Statistical equivalence.

2. The limits of centrality measures.

3. Symptoms can be latent variables.

4. The problem of reductionism.

5. Where is the social?

6. Timing, dynamics and time scales.

7. Reproducibility and replicability.

8. Therapeutically targeting symptoms.

 

Why Embrace this Approach?

 

Within the soft transdiagnostic camp, the symptom network approach is, for us, the more viable route for those interested in the study of social complexity. And we say this despite the fact that this approach has some considerable challenges to address – which we just listed. Here is our rationale:

 

First and foremost, given its grounding in the complexity sciences, the network approach to psychopathology fits with the theoretical synthesis we have so far stitched together.

 

Second, this approach avoids the trap that the hierarchical latent variable approach falls into, given that the latter is still, ironically enough, in search of a more fundamental set of causal factors to explain mental disorders.

 

Third, while we appreciate the hard transdiagnostic camp’s attempt to revolutionise diagnostic nomenclature, its argument is doomed. It will never happen.

 

Finally, despite the flaws of the network approach, we will show that its problems can be fixed, oddly enough, by making better use of complex networks.

 

Our approach in Chapter 14 is to sidestep the theoretical shallowness of symptom networks by embracing a hierarchical network approach, which stiches together not only the biological and neuropsychological levels of human psychology but also, moving into the next major section of the Atlas, the social.

 

Still, despite the advances made by the symptom network literature, the social is still deafeningly missing from everyone’s work. Transdiagnostic approaches need to stop treating the social as a trigger for psychopathology, and see it, instead, as core to its formation. 

 

 

 

KEY WORDS: symptom networks, psychopathology, network theory, psychometrics, transdiagnostic psychiatry and psychology, network science of mental disorders.



[1] Angélique O. J. Cramer et al., ‘Comorbidity: A Network Perspective’, Behavioral and Brain Sciences 33, no. 2–3 (June 2010): 137–50.

[2] Donald J. Robinaugh et al., ‘The Network Approach to Psychopathology: A Review of the Literature 2008–2018 and an Agenda for Future Research’, Psychological Medicine 50, no. 3 (February 2020), .p. 353.

[3] Ibid., p. 353.

[4] In reality, the paper was accepted for publication in 2017, and the commentaries and paper were collected and published online by Cambridge University Press: 24 January 2018, e2, but the final formal version was 2019.

26/10/2024

The Atlas of Social Complexity. Chapter 13: Human psychology as dynamical system

As I stated in my previous post, the second major content theme in The Atlas of Social Complexity is the Dynamics of Human Psychology. In my previous post I provided a quick summary of the theme.

 

The focus of this post is the first chapter in this theme, Human psychology as dynamical system (Chapter 13).

 

 

SUMMARY OF CHAPTER

Our theme on human psychology begins with the basic question: How best should we view the human condition? Is there really a definitive answer to this question? No, there is not. But, for sure, at least for the purposes of scientific inquiry, some answers seem better suited or more applicable, particularly for helping us out of certain path dependencies in thinking and treating people.

 

Dynamical systems theory is just such an answer, as it not only provides a different view of human psychology, but it also overcomes many of the limitations in thinking that current conventional approaches in statistical and qualitative methods cannot, on their own, get past.

 

Still, as we have already indicated, that does not mean it lacks its own problems. For mathematicians and non-mathematicians alike, dynamical systems theory is by no means an easy-going field of study. Some of its areas of research – chaos theory, swarm behaviour, complexity science – have certainly become part of mainstream culture, and the visualisation of these ideas is amazingly intuitive, allowing non-experts access to some of its key ideas. But serious study of human behaviour as an evolving dynamic system is hard work that requiring significant transdisciplinary engagement amongst mathematicians and social scientists working together at the intersection of complexity, methods, and psychology. Otherwise, this field can fall prey to many of the traps created by the thirteen challenges – in fact, in many ways, it is presently struggling with these challenges, as we shall see in a moment. The research we will review here, then, points to an adjacent possible, a potential way out.

 

This chapter first introduces the main the mathematical concepts central to the field, from bifurcation points to continuous dynamical systems; and, second, surveys dynamical psychology’s nine core realities about human psychology. The goal is to point readers toward the most promising research in this transdisciplinary area of social complexity.

 

 

KEY WORDS: Dynamical systems theory, dynamical psychology, differential equations, continuous dynamical system, differential equations, synergetics and psychology.


20/10/2024

Improving climate change resilience in healthcare: Japan and the UK Workshop hosted by AMS and JSPS.

I would like to thank the UK Academy of Medical Sciences (AMS) International Policy Arm and the Japan Society for the Promotion of Science (JSPS) London for the opportunity to present and participate in their two-day international policy workshop.

 

The workshop focus was on Improving the resilience of health and public health systems to the impact of climate change: learning between Japan and the UK.

 

OVERVIEW OF MY TALK

My talk focused on two things.

 

1.  Developing interdisciplinary methods that facilitate a more in-depth understanding of healthcare resilience in the face of climate change.

 

2.    Applying these to my particular topic area: EnvironMental Health and the Exposome, with a particular focus on place and living in complex systems.

 

 

For my talk, I introduced COMPLEX-IT, the R shiny platform that my colleagues and I developed, which is free for online use or downloading to run in R Studio.

  • For more on our work on EnvironMental Health and the Exposome, see our research and policy consortium, InSPIRE.

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I also had the chance to then attend, on the last day, the  AMS & The Lancet-International Health Lecture 2024 on “Climate crisis, cities and health” on 17 October, delivered by Prof Mark J Nieuwenhuijsen, who is Research Professor and Director of the Urban Planning, Environment and Health Initiative, and Director of the Air pollution and Urban Environment Programme at ISGlobal in Barcelona Spain. The manuscript of the lecture has now been published in The Lancet online: Climate crisis, cities, and health - The Lancet. A video of the lecture can be found here.

 


16/10/2024

The Atlas of Social Complexity. Content Theme 2: The Complex Dynamics of Human Psychology

As I stated in my previous post, the first major content theme in The Atlas of Social Complexity is Cognition, Emotion and Consciousness. This first theme includes six chapters, which I have so far blogged on. Chapter 6 addresses autopoiesis. Chapter 7 turns to the role of bacteria in human consciousness. Chapter 8 explores how the immune system, just like bacteria and cells, is cognitive – and the implications this has for our wider brain-based consciousness. Chapter 9 explores a complexity framing of brain-based cognition, emotion and consciousness. Chapter 10 explores the complex multilevel dynamics of the Self. Chapter 11 is about human-machine intelligence.

 

The second content theme concerns the dynamics of human psychology. Here is a quick summary of the theme.

 

COMPLEX PSYCHOLOGY

There is no defined field of study called complex psychology. There are only somewhat different areas of research that could be connected – although, there is the whisper of a theoretical framework, namely dynamical systems theory. This lack of explicit awareness and synthesis puts the study of psychological complexity at a disadvantage because most psychologists and complexity scientists draw on only parts of the field. Our tour seeks to remedy this problem by taking readers on a journey through this research and synthesising them into a working complex psychology.

 

This theme is comprised of four chapters:

  • Human psychology as dynamical system (Ch 13)
  • Psychopathology of mental disorders (Ch 14)
  • Healing and the therapeutic process (Ch 15)
  • Mindfulness, imagination and creativity (Ch 16)

 

These chapters follow, in order, four key questions these scholars ask in their work. Chapter 13 begins with the most fundamental: How best should we view the human condition?  Chapter 14 asks: What is a mental disorder and how best should we measure and assess it? Chapter 15 asks: What does complexity have to say about the healing and therapeutic process? And, finally, Chapter 16 asks: What can the study of social complexity say about the positive aspects of our human psychology, and the power and healing potential of mindfulness, imagination, and creativity?

 

CLICK HERE to purchase the book, or to request it for your library.

 

 

KEY WORDS: dynamical psychology, symptom networks, dynamics of therapy, psychopathology, mindfulness, creativity.

07/10/2024

The Atlas of Social Complexity. Chapter 11: Human-Machine

As I stated in my previous post, the first major content theme in The Atlas of Social Complexity is Cognition, Emotion and Consciousness.

  • Chapter 6 addresses autopoiesis.
  • Chapter 7 turns to the role of bacteria in human consciousness.
  • Chapter 8 explores how the immune system, just like bacteria and cells, is cognitive – and the implications this has for our wider brain-based consciousness.
  • Chapter 9 explores a complexity framing of brain-based cognition, emotion and consciousness.
  • Chapter 10 explores the complex multilevel dynamics of the Self. 
  • Chapter 11, the final one for this section and the focus of the current post, is about human-machine intelligence.

CLICK HERE to purchase the book, or to request it for your library.

 

HUMAN-MACHINE, A quick summary

AI is everywhere today. And it happened quickly. What does it all mean for human consciousness?

As we navigate the Digital Anthropocene, AI and technology provoke critical questions about how our cognition, emotions, and awareness are evolving alongside these new technologies. In particular, they raise quesdtions about the current development and future evolution (as a species) of our cognition, emotion and consciousness in relation to technological systems. Chapter 11 of the Atlas explores these questions. Our guide for this journey is the American literary critic and posthumanist scholar, Katherine Hayles, and her theory of human-technical cognitive assemblages, as outlined in her book, Unthought.

To put Hayles’ framing to work, we do three things in this chapter.

  • We define what she means by human-technical cognitive assemblages.
  • We rework her definition of machine cognition to better align it with the study of social complexity.
  • We set the stage for Chapter 22, in which we spend considerable time exploring our current complex system of systems of digital machines and our posthuman condition.

Here is a glimps at some of our conclusions from this chapter.

The inability of machine cognition to explain itself is why scholars refer to machine learning as a ‘black box’. We know how to programme machine cognition using artificial neural nets, genetic algorithms or computational models; but we often have little insight into how machine cognition arrives at its conclusions because these machine are ignorant of what they do, beyond the output they provide and the data upon which they are trained. Case in point is Cliff Kuang’s New York Times article, Can A.I. be taught to explain itself?[1] In the article, Kuang explains that “as machine learning becomes more powerful, the field’s researchers increasingly find themselves unable to account for what their algorithms know – or how they know it”. 

This gets to a core problem of nonconscious cognition: while it extends our cognitive and emotional life and our consciousness to a near global level, it still requires a significant degree of attendant human intelligence, involvement, management, guidance, or control. This core problem also points to a wider and as yet unaddressed problem in our travels: complexity. Machine cognition is very good at ‘difficult’ and ‘complicated’, processing information and large amounts of data, in brute force, at speeds that are humanly impossible; but human cognition is still better at complexity. Winning at chess is one thing, but winning in diplomacy is another. Human consciousness needs to retain is executive function. The Self evolved and emerged for a reason: complex living systems, even when their embodiment is extended to the mechanical and digital, require guidance, even when that executive function is limited by its own consciousness.

Or at least for now.

What we will become, as posthuman cyborgs, over the course of the several hundred years, given our increasing integration into and cognitive dependency upon a global network of human-machine cognitive assemblages, is difficult to determine. One thing, however, is for sure: any exhaustive study of human cognition, emotion and consciousness needs to contend, at some point, with this newly emerging form of human evolution, as we move through the early stages of the Digital Anthropocene.


KEY WORDS: Machine cognition, actor network theory, new materialism, posthumanism, transhumanism, human-technical cognitive assemblages.


28/09/2024

The Atlas of Social Complexity. Chapter 10: The Self

As I stated in my previous post, the first major content theme in The Atlas of Social Complexity is Cognition, Emotion and Consciousness.

 

Chapter 6 addresses autopoiesis.

Chapter 7 turns to the role of bacteria in human consciousness.

Chapter 8 explores how the immune system, just like bacteria and cells, is cognitive – and the implications this has for our wider brain-based consciousness.

Chapter 9 explores a complexity framing of brain-based cognition, emotion and consciousness.

Chapter 10 – the current post – explores the complex multilevel dynamics of the Self. 


THE SELF, A quick summary

The Self is a milestone in the evolution of consciousness. One can think of The Self, be it at any level, as some form of executive function consciousness through which an organism recognises itself and its environment. For some social animals, The Self has evolved from a very primitive, primordial form into more complex dynamics, based on the evolutionary power of social life, and with the human self being the most complex.

 

As shown in Figure 1, Chapter 10 reviews the literature on the human self and its multiple forms and levels, including

  • primordial-self, 
  • reflexive-self
  • autobiographical-self
  • social-self
  • public-self

 

 

Chapter 10 also explores how The Self exists as much for the body as it does for the agency of our self-reflecting mind, the emotional core out of which The Self emerges; and, finally, how The Self exists for others in our complex social worlds, including our outward facing public-self. Authors include Damasio, Temple Grandin and Jaak Panksepp on the primordial self and the role of emotions and feeling in mind self and consciousness; Merleau-Ponty and Evan Thompson on the self, cognition, and embodiment; Freud and symbolic interactionism on the reflexive self; and Satre and Mead on the social and public self.

 

 

KEY WORDS: The self, primordial-self, reflexive-self, autobiographical-self, social-self, public-self.


18/09/2024

The Atlas of Social Complexity. Chapter 9: Brain-based cognition, emotion and consciousness

As I stated in my previous post, the first major content theme in The Atlas of Social Complexity is Cognition, Emotion and Consciousness. Chapter 6 addresses autopoiesis. Chapter 7 turns to the role of bacteria in human consciousness. Chapter 8 explores how the immune system, just like bacteria and cells, is cognitive – and the implications this has for our wider brain-based consciousness. Chapter 9 -- the focus of the current post -- explores a complexity framing of brain-based cognition, emotion and consciousness.

 

Brain-based cognition, emotion and consciousness

 

Over the last two decades, the cognitive, neurological and psychological sciences have made major progress in our understanding of mind/brain and its links with our embodied existence.

If ever a topic screamed for a complexity theory, then brain-based cognition would be at the top of the list!

 

But first some hard theoretical and empirical work needs to be done. In this chapter we use a social complexity framework to sort our position vis-à-vis six major debates within the field:

  • cognition and life
  • the mind/brain dualism
  • the unconscious
  • modularity
  • emotions
  • brain-based consciousness

With these issues sorted, we then outline the contours of a new complex systems theory of consciousness, which serves as a framework for the rest of our tour. 

 

KEY WORKDS: brain-based cognition, emotions, the emotional self, embodied mind, cognitive unconscious, consciousness, modularity, paleomammalian emotions.


05/09/2024

The Atlas of Social Complexity. Chapter 8: Immune System Cognition

As I stated in my previous post, the first major content theme in The Atlas of Social Complexity is Cognition, Emotion and Consciousness. Chapter 6 addresses Autopoiesis. Chapter 7 turns to the role of bacteria in human consciousness. Chapter 8 (Immune System Cognition), which is our focus here, explores how the immune system, just like bacteria and cells, is cognitive – and the implications this has for our wider brain-based consciousness.

 

THE IMMUNE SYSTEM SELF

Figure 1: Macrophages attacking cancer cell (the large, spiky mass). Upon fusing with the cancer cell, the macrophages (smaller white cells) inject toxins that kill the tumour cell. Immunotherapy for the treatment of cancer is an active area of medical research. By Raowf Guirguis and Susan Arnold.[1]



[1] National Institutes of Health, National Cancer Institute, Visuals Online. https://visualsonline.cancer.gov/details.cfm?imageid=2370 accessed 5 March 2023.

 

As everyone who has taken a biology class learns, the founding principal of immunology is the concept of ‘identity’ and the capacity of immune systems to distinguish between self and non-self. While the immune system functions at a different level of consciousness than our brain-based self, it is nonetheless continually engaged in a complex set of cognitive processes that are in constant communication with our body’s various cognitive systems and agents, including the microbiota-gut-brain axis. (For further reading, see Klenerman, Paul. The Immune System: A Very Short Introduction. Oxford: Oxford UP, 2017)

In this chapter, after a brief introduction to the immune system, we explore the leading-edge view of immunity that not only resonates with the research elsewhere in Theme 2 but is also fundamentally reshaping our understanding of the immune system’s complex relationship with its environment and how this relationship can be harnessed to treat disease and infection more effectively. This approach is called ecoimmunology.

 

That is not to say the field of ecoimmunology is without controversy or internal debate, because it is. In response, we end Chapter 8 recommending what readers take away from the debates within immunology around issues of cognition, identity, memory and the self; and what research direction we think most useful for the theoretical weave we seek to construct. 


Here is a short summary of our recommendations:

  • First, we strongly recommend embracing eco-immunology.
  • Second, to address the ‘immune self and cognition’ debate, we recommend not taking a side. Instead, we advocate for combining approaches. It is of significant irony that the mainstream representational approach – being current scientific convention – embraces a complex systems view of the immune self; while complex systems scholars such as Maturana, Varela, Jerne and Tauber disagree with it.
  • A useful example of combining approaches is the two-tier schema developed by António Coutinho, the Portuguese immunologist, and Francisco Varela, in combination with their colleagues at the Paris school they helped to create.[1]
  • Third, we recommend integrating the representational immune self with eco-immunology, while dropping the Jerne and Varela self/nonsense distinction.
  • Fourth, we recommend embracing Tauber’s argument that the immune system self, like most complex systems, lacks a centralised command centre and therefore a centralised identity.
  • Fifth, the immune system is not without hierarchy.
  • Finally, we recommend the representational view that immune systems do, in varying degrees, represent things, see things, learn things, hold memory, and remember things. We see no compelling evidence to think otherwise. If the mind is in every cell of the body, then it only makes sense it resides in the immune system as well.

 

KEY WORDS: Immune system cognition, eco-immune system, ecoimmunology, representational immune self, cellular cognition, bacterial cognition.



[1] Coutinho, A. Biological research. 2003: 36(1), 17-26.